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Mr McCondichie

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DNA and Inheritance

Lesson 1 - What is a species?

Learning Intentions

Cells Recap

DNA

In this unit we are going learn more about this DNA, what it's job is and why it is so important.

Watch the video below to find out more.

Species

Infertile Offspring

Activity - Hybrids

Animals that are born from parents that are different species (like a mule) are called hybrids. They are infertile.

Can figure out which animals were involved in creating the following hybrids?

______ + Shetland Pony = Zebrony

Grizzly Bear + __________ = Grolar Bear

Cow + _________ = Beefalo

Camel + _____ = Cama

Serval + ______ = Savannah Cat

________ + Goat = Geep

My favourite example of a hybrid is ___________ it is created from a _________ and a __________

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Lesson 2+3 - Variation

Learning Intentions

Variation

Although members of the same species are very similar to one another they are not identical. This is because variation exists within a species.

Variation is the differences between members of the same species

Watch the clip below on variation.

Spot the Difference

Activity - What differences exist between humans?

Copy the table below into your notes.

Use your table to record the different eye colours of people in your class.

Copy the table below into your notes.

Use your table to record the number of tounge rollers in your class.

Copy the table below into your notes.

Use it to record the hand span of people in your class.

Draw a bar graph of at least one of your tables.

Draw a line graph of at least one of your tables.

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Lesson 4 - DNA Structure

Learning Intentions

Notes - Inside the Nucleus

Notes - DNA

Note - Base Pairs

DNA has 4 different bases along the strands

Note - Important

Adenine and Thymine always join together

Cytosine and Guanine always join together

Activity - Lets Practice

What would be the matching strand for this piece of DNA?

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Lesson 5 - DNA Models

Learning Intention

DNA models

We are going to create origami models of DNA.

To get them to work we have to be careful how we colour it in and how we fold them.

You will need to download and print a template to do this avtivity.

Click on the pdf symbol below to download a template.

OR

Click on the word symbol to download a template.

Instructions

Note: all folds should have a thin line on the inside and a think line on the outside.

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Lesson 6 - DNA Extraction

Learning Intention

Activity - Extracting DNA from Strawberries

Watch the video below on extracting DNA from strawberries.

Instructions

  1. Place one strawberry in a poly bag.
  2. Keeping the top closed, pulp the strawberry for 2 minutes.
  3. Using 10 ml measuring cylinder, add 10 ml extraction buffer to the bag.
  4. Mush again for 1 minute.
  5. Filter through tea strainer into beaker.
  6. Pour 1 - 2 cm of filtrate into a test tube.
  7. Tilt the test tube and slowly pipette ice cold alcohol into the neck of the test tube, so that it 'floats' on the strawberry filtrate, until the test tube is half full.
  8. After several minutes, tiny crystals of DNA should precipitate out of solution at the interface. The DNA can be spooled out on the tip of a glass rod or wooden splint.

Questions on Extracting DNA from Strawberries

  1. Why do we crush the strawberries?
  2. What does the extraction buffer do?
  3. Why do we filter the mushed up strawberry and buffer?
  4. Why do we add alcohol?

DNA Recap

Watch the video below to recap what you have learned so far about DNA.

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Lesson 7 - Function of DNA

Learning Intentions

DNA is a code!

The order of the bases creates a code. This code is used as the instructions to make protein. Although there are only 4 bases, they can make lots of different proteins e.g.

ATTCGGTCATGA codes for blue eyes:

ATTCGCTCATGA codes for green eyes:

Think about a cake....

The recipe is the instructions that tell you what ingredients to use to make the cake.

In a cell DNA is the instructions for how to make a protein.

DNA to Proteins

Proteins are made from amino acids. The sequence of bases is read by the cell in groups of 3. This tells the cell what amino acids to use to make the protein

Activity - Cracking the Code

You are going to act like the cell and try to read DNA sequences

Each group of 3 bases will represent a particular amino acid

The amino acids match to letters which can then be put together to provide a secret spy note

Can you crack the code and save the world???

How to read the code......

We read the code in groups of 3 bases read from the inner circle out.

So if we had TTG the amino acid would be leucine.

Now that we know the amino acid we can match it to a letter

Leucine would be an L

Practice

What would be the amino acid and letter for the following?

Now try cracking the code:

Greetings, Agent

Intelligence sources have revealed to us that the terrorist organisation CLONE (Conspiracy to Liberate Obnoxious and Nasty Enemies) is preparing to threaten the free World with a terrible and secret plot. Our agents have intercepted several messages from CLONE which we believe may contain information about this dreaded plot. Unfortunately, all of the messages are written in the insidious GENETIC CODE.

Your mission is to translate the codes, using the code key provided. Fill in the correct single-Letter abbreviation for the amino acid that is coded by each triplet. Good Luck!

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Lesson 8 - DNA Profiling

Learning Intention

DNA Fingerprinting

Watch the video below on how DNA fingerprinting is used.

DNA Profiling

DNA profiling/DNA fingerprinting has many uses

Forensics

DNA can be used to help with investigations to identify and eliminate suspects:

Paternity testing

DNA can be used to find out who the biological father of a child is:

Genetic testing

DNA can be used to work out if someone has inherited a genetic disease:

Food Fraud

DNA can be used to identify the source of meat in supermarket ready meals:

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Lesson 9 - Reproduction

Learning Intentions

Reproduction

Think about the following:

  1. What is reproduction?
  2. Is it important?
  3. Why?

Notes - Reproduction

Reproduction is the production of new members of a species.

For a species to survive, it must produce enough young to replace those that die.

Sexual Repreoduction

Sexual reproduction needs two parents. Each parent has to produce special sex cells, which are made in the sex organs (reproductive system).

Sex Cells

Watch the video below on the male and female sex cells.

Notes - Sex Cells

Animals have specialist cells for reproduction.

The Male Reproductive Organs

Copy the diagram into your notes.

Female Reproductive Organs

Copy the diagram below into your notes.

Complete the following table and stick it into your notes.

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Lesson 10 - Fertilisation

Learning Intentions

Fertilisation

After intercourse sperm are released into the vagina and their epic journey begins. Click on the picture to see this journey.

The Journey to the Egg

Fertilisation occurs when the nucleus from the sperm joins with the nucleus of the egg.

Notes - Fertilisation

When the head of one sperm gets into the egg, the male nucleus fuses with the female nucleus. This is fertilisation.

The fertilised egg now has a complete set of DNA. 23 chromosomes from the male and 23 chromosomes from the female.

What happens next?

The newly fertilised egg is now known as an embryo.

Watch the video below to see this process.

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Lesson 11 - Pregnancy

Learning Intentions

Pregnancy

In humans pregnancy lasts approximately 40 weeks. In this time the embryo that started out as a single cell will develop all the characteristics that make us human. The average weight at birth 7.7lbs (3.5kg). Pregnancy is split into 3 stages called trimesters each lasting approximately 3 months.

First Trimester

Watch the video below on the first trimester.

Second Trimester

Watch the video below on the second trimester.

Third Trimester

Watch the video below in the third trimester

Development of the Foetus

Label the diagram using the words below.

Foetus

Placenta

Umbilical Cord

Amniotic Sac

Notes - Pregnancy

Pregnancy in humans lasts 40 weeks. While in the uterus the p_______ provides the foetus with food and oxygen from the mother and takes away waste materials.

Questions - Pregnancy

  1. How long is a human pregnancy?
  2. How many trimesters are there?
  3. What is the purpose of the placenta?
  4. What is the purpose of the amniotic sac?
  5. At what point in pregnancy is an embryo known as a foetus?

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Lesson 12 - Risks to Embryo

Learning Intentions

Risks to the Embryo

Copy the spider diagram below into your notes

Download the file below on risks to the embryo.

Click on the pdf symbol below to download the file.

OR

Click on the word symbol to download the file.

Use the information in the document to help you complete your spider diagram.